Investigation into conolidine has led to discovery of the opioid receptor in your body called ACKR3/CXCR7. ACKR3 is apparently one of the most wanted target for conolidine, which also disregards another 4 classical opioid receptors(3). There's interest in making use of conolidine being a pain-reliever determined by proof from https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers