In this article, we show that conolidine, a normal analgesic alkaloid Employed in conventional Chinese drugs, targets ACKR3, thereby furnishing more proof of a correlation concerning ACKR3 and ache modulation and opening alternate therapeutic avenues to the therapy of Continual agony. Utilized in common Chinese, Ayurvedic, and Thai drugs. https://andyv738ndu4.glifeblog.com/profile