An extensive literature critique of research amongst 1995 and 2018 was carried out utilizing the electronic databases PubMed and EBSCO Host. Queries have been executed making use of the subsequent conditions: total knee arthroplasty (TKA); cyclooxygenase-two inhibitors; bracing; Bodily therapy; weight loss; knee; treatment; therapeutics; OA; intra-articular injection; hyaluronic acid; https://www.theorthopaedicandpainpractice.com/non-surgical-treatments-for-knee-joint-pain/