In this article, we display that conolidine, a natural analgesic alkaloid Utilized in common Chinese medication, targets ACKR3, thereby providing additional evidence of a correlation involving ACKR3 and discomfort modulation and opening choice therapeutic avenues with the treatment of chronic discomfort. The 1st asymmetric full synthesis of conolidine was https://immanuelm945efc6.blogunteer.com/profile